Enabling advanced tissue fabrication
The PGbioInk system facilitates robust bio-ink design and production suitable for a variety of cell performance to meet the needs of advanced tissue biofabrication via 3D bioprinting techniques. Bio-ink selection has severely limited the advancement of bioprinting for human tissue, organs, and regenerative medicine. Each cell type requires a specific microenvironment for living. A biomaterial good for cells may not meet the bio-ink specifications or vice versa. PGbioInk is the home for cells; it is biocompatible, so-gel reversible by shearing force, and makes for easy loading of cells, nutrients, growth factors, dugs, and other small molecules at room or body temperatures.
The advancement of 3D printing provides tremendous opportunities to produce complicated biological organs for improving human health by reparation or replacement. To date, the grand challenge is still that of mimicking the natural extracellular matrix (ECM), a 3D network matrix composed of fibrous matrix proteins that provides structural integrity for cellular anchorage and naturally sequesters soluble signals that direct cell performance, with a system that can be handled at room conditions and that has the desirable mechanical and viscoelastic properties for 3D bioprinting.
With these unique features, PGbioInk offers the best biocompatible hydrogel for the surface coating of 3D printed scaffolds.
- Universal Peptide Hydrogel for Scalable Physiological Formation and Bioprinting of 3D Spheroids from Human Induced Pluripotent Stem Cells, Advanced Functional Materials, 2021, Vol 31, Issue 41.
- 3D-printing enabled micro-assembly of a microfluidic electroporation system for 3D tissue engineering, Lab Chip, 2019, 19, 2362.