PGmatrix News
Overview PGmatrix™ Injection in vivo delivery systems are transforming regenerative medicine by providing localized, sustained, and physiologically relevant environments for cell and tissue repair. PGmatrix Injection’s tissue-like mechanics, xeno-free composition, and tunable release kinetics support the delivery of therapeutic compounds in a controlled, targeted, and safe manner PGmatrix hydrogels are physiologically defined peptide hydrogels that […]
No. 0001 PGmatrixTM Enables Physiologically Relevant 3D Tumor Organoids
Overview Tumor organoid models are vital tools for drug discovery and development, and for translational cancer research. Conventional 2D or 3D cell aggregates in suspension systems often fail to capture the physiological complexity of tumor growth. PepGelTM PGmarix™ hydrogel provides a biomimetic extracellular matrix (ECM) that supports natural tumor architecture and function in vitro, closely […]
No. 0002 PGmatrixTM Enables 3D hiPSC Maintenance, Expansion, and Bioprinting
Overview Human induced pluripotent stem cells (hiPSCs) are fundamental to regenerative medicine, drug discovery, and disease modeling. Conventional 2D culture systems fail to replicate the physiological microenvironment necessary to maintain pluripotency, leading to reduced differentiation potential. This case study highlights PepGel’s PGmatrix™ system, a well-defined, xeno-free peptide hydrogel that provides a physiologically authentic 3D microenvironment […]
No. 0003 PGmatrixTM Cells Enables Lumen Cyst Formation within MDCK Organoids
Introduction Madin-Darby Canine Kidney (MDCK) cells are a widely used epithelial cell line in biomedical research and biotechnology due to their well-characterized morphology, robust growth, and ability to form polarized monolayers. Traditionally, MDCK cells are cultured in 2D monolayers, serving as a model for viral propagation (e.g., influenza vaccine production), drug permeability, and epithelial barrier […]
No. 0004 PGmatrix™ Injection for Regenerative Medicine
Overview PGmatrix™ Injection in vivo delivery systems are transforming regenerative medicine by providing localized, sustained, and physiologically relevant environments for cell and tissue repair. PGmatrix Injection’s tissue-like mechanics, xeno-free composition, and tunable release kinetics support the delivery of therapeutic compounds in a controlled, targeted, and safe manner PGmatrix hydrogels are physiologically defined peptide hydrogels that […]