Welcome to PepGel - cellular biomimicry

No. 0002 PGmatrixTM Enables 3D hiPSC Maintenance, Expansion, and Bioprinting

Overview Human induced pluripotent stem cells (hiPSCs) are fundamental to regenerative medicine, drug discovery, and disease modeling. Conventional 2D culture systems fail to replicate the physiological microenvironment necessary to maintain pluripotency, leading to reduced differentiation potential. This case study highlights PepGel’s PGmatrix™ system, a well-defined, xeno-free peptide hydrogel that provides a physiologically authentic 3D microenvironment […]

No. 0003 PGmatrixTM Cells Enables Lumen Cyst Formation within MDCK Organoids

Introduction Madin-Darby Canine Kidney (MDCK) cells are a widely used epithelial cell line in biomedical research and biotechnology due to their well-characterized morphology, robust growth, and ability to form polarized monolayers. Traditionally, MDCK cells are cultured in 2D monolayers, serving as a model for viral propagation (e.g., influenza vaccine production), drug permeability, and epithelial barrier […]

No. 0004 PGmatrix™ Injection for Regenerative Medicine

Overview PGmatrix™ Injection in vivo delivery systems are transforming regenerative medicine by providing localized, sustained, and physiologically relevant environments for cell and tissue repair. PGmatrix Injection’s tissue-like mechanics, xeno-free composition, and tunable release kinetics support the delivery of therapeutic compounds in a controlled, targeted, and safe manner PGmatrix hydrogels are physiologically defined peptide hydrogels that […]